Drugs that activate or modify the immune system to attack cancer cells. Checkpoint inhibitors (targeting PD-1, PD-L1, CTLA-4) are the most common.
BAVENCIO · Avelumab
EMD Serono, Inc. Programmed Death Ligand-1 Blocker [EPC] · Programmed Death Ligand-1 Antagonists [MoA]
From the FDA label: 1 INDICATIONS AND USAGE BAVENCIO is a programmed death ligand-1 (PD-L1) blocking antibody indicated for: Merkel Cell Carcinoma (MCC) Adults and pediatric patients 12 years and older with metastatic MCC. ( 1.1 , 14.1 ) Urothelial Carcinoma (…
IMFINZI · Durvalumab
AstraZeneca Pharmaceuticals LP Programmed Death Ligand-1 Blocker [EPC] · Programmed Death Ligand-1 Antagonists [MoA]
From the FDA label: 1 INDICATIONS AND USAGE IMFINZI is a programmed death-ligand 1 (PD-L1) blocking antibody indicated: • in combination with platinum-containing chemotherapy as neoadjuvant treatment, followed by IMFINZI continued as a single agent as adjuvant…
OPDIVO · Nivolumab
E.R. Squibb & Sons, L.L.C. Programmed Death Receptor-1 Blocking Antibody [EPC] · Programmed Death Receptor-1-directed Antibody Interactions [MoA]
From the FDA label: 1 INDICATIONS AND USAGE OPDIVO is a programmed death receptor-1 (PD-1)-blocking antibody indicated for the treatment of: Melanoma • adult and pediatric (12 years and older) patients with unresectable or metastatic melanoma, as a single agen…
OPDIVO QVANTIG · Nivolumab And Hyaluronidase-Nvhy
E.R. Squibb & Sons, L.L.C. Programmed Death Receptor-1 Blocking Antibody [EPC] · Endoglycosidase [EPC]
From the FDA label: 1 INDICATIONS AND USAGE OPDIVO QVANTIG is a combination of nivolumab, a programmed death receptor-1 (PD-1)-blocking antibody, and hyaluronidase, an endoglycosidase, indicated for the treatment of: Renal Cell Carcinoma (RCC) • adult patients…
KEYTRUDA · Pembrolizumab
Merck Sharp & Dohme LLC Programmed Death Receptor-1 Blocking Antibody [EPC] · Programmed Death Receptor-1-directed Antibody Interactions [MoA]
From the FDA label: 1 INDICATIONS AND USAGE KEYTRUDA is a programmed death receptor-1 (PD-1)-blocking antibody indicated: Melanoma for the treatment of patients with unresectable or metastatic melanoma. ( 1.1 ) for the adjuvant treatment of adult and pediatric…
KEYTRUDA QLEX · Pembrolizumab And Berahyaluronidase Alfa-Pmph
Merck Sharp & Dohme LLC Endoglycosidase [EPC] · Programmed Death Receptor-1 Blocking Antibody [EPC]
From the FDA label: 1 INDICATIONS AND USAGE KEYTRUDA QLEX is a combination of pembrolizumab, a programmed death receptor-1 (PD-1)-blocking antibody, and berahyaluronidase alfa, an endoglycosidase, indicated: Melanoma for the treatment of adult patients with un…