Drugs whose pharmacologic class was not automatically classified into the groups above. Check the FDA label for mechanism details.
Rylaze · Asparaginase Erwinia Chrysanthemi (Recombinant)-Rywn
Jazz Pharmaceuticals, Inc. Asparagine-specific Enzyme [EPC] · Asparaginase [CS]
From the FDA label: 1 INDICATIONS AND USAGE RYLAZE is indicated as a component of a multi-agent chemotherapeutic regimen for the treatment of acute lymphoblastic leukemia (ALL) and lymphoblastic lymphoma (LBL) in adult and pediatric patients 1 month or older w…
ONUREG · Azacitidine
Celgene Corporation Nucleoside Metabolic Inhibitor [EPC] · Nucleic Acid Synthesis Inhibitors [MoA]
From the FDA label: 1 INDICATIONS AND USAGE ONUREG is indicated for continued treatment of adult patients with acute myeloid leukemia who achieved first complete remission (CR) or complete remission with incomplete blood count recovery (CRi) following intensiv…
BLINCYTO · Blinatumomab
Amgen, Inc From the FDA label: 1 INDICATIONS AND USAGE BLINCYTO is a bispecific CD19-directed CD3 T-cell engager indicated for the treatment of adult and pediatric patients one month and older with: CD19-positive B-cell precursor acute lymphoblastic leukemia (ALL) in fir…
asparlas · Calaspargase Pegol
Servier Pharmaceuticals LLC Asparagine-specific Enzyme [EPC] · Asparaginase [CS]
From the FDA label: 1 INDICATIONS AND USAGE ASPARLAS is an asparagine specific enzyme indicated as a component of a multi-agent chemotherapeutic regimen for the treatment of acute lymphoblastic leukemia in pediatric and young adult patients age 1 month to 21 y…
Clofarabine · Clofarabine
Amneal Pharmaceuticals LLC Nucleoside Metabolic Inhibitor [EPC] · Nucleic Acid Synthesis Inhibitors [MoA]
From the FDA label: 1 INDICATIONS AND USAGE Clofarabine injection is indicated for the treatment of pediatric patients 1 to 21 years old with relapsed or refractory acute lymphoblastic leukemia after at least two prior regimens. Clofarabine injection is a nucl…
Idhifa · Enasidenib Mesylate
Celgene Corporation From the FDA label: 1 INDICATIONS AND USAGE IDHIFA is an isocitrate dehydrogenase-2 inhibitor indicated for the treatment of adult patients with relapsed or refractory acute myeloid leukemia (AML) with an isocitrate dehydrogenase-2 (IDH2) mutation as detected
RELEUKO · Filgrastim
Amneal Pharmaceuticals LLC Leukocyte Growth Factor [EPC] · Granulocyte Colony-Stimulating Factor [CS]
From the FDA label: 1 INDICATIONS AND USAGE RELEUKO is a leukocyte growth factor indicated to: Decrease the incidence of infection‚ as manifested by febrile neutropenia‚ in patients with nonmyeloid malignancies receiving myelosuppressive anti- cancer drugs ass…
Nivestym · Filgrastim-Aafi
Pfizer Laboratories Div Pfizer Inc Leukocyte Growth Factor [EPC] · Granulocyte Colony-Stimulating Factor [CS]
From the FDA label: 1 INDICATIONS AND USAGE NIVESTYM is a leukocyte growth factor indicated to • Decrease the incidence of infection‚ as manifested by febrile neutropenia‚ in patients with nonmyeloid malignancies receiving myelosuppressive anti-cancer drugs as…
ZARXIO · Filgrastim-Sndz
Sandoz Inc. Leukocyte Growth Factor [EPC] · Granulocyte Colony-Stimulating Factor [CS]
From the FDA label: 1 INDICATIONS AND USAGE ZARXIO is a leukocyte growth factor indicated to • Decrease the incidence of infection‚ as manifested by febrile neutropenia‚ in patients with nonmyeloid malignancies receiving myelosuppressive anti‑cancer drugs asso…
NYPOZI · Filgrastim-Txid
Cipla USA Inc. Leukocyte Growth Factor [EPC] · Granulocyte Colony-Stimulating Factor [CS]
From the FDA label: 1 INDICATIONS AND USAGE NYPOZI is a leukocyte growth factor indicated to: Decrease the incidence of infection, as manifested by febrile neutropenia, in patients with nonmyeloid malignancies receiving myelosuppressive anti-cancer drugs assoc…
Fludarabine Phosphate · Fludarabine Phosphate
Lannett Company, Inc. From the FDA label: 1 INDICATIONS AND USAGE Fludarabine Phosphate Injection is a nucleotide metabolic inhibitor indicated for: The treatment of adult patients with B-cell chronic lymphocytic leukemia (CLL) who have not responded to or whose disease has progres…
Daurismo · Glasdegib
Pfizer Laboratories Div Pfizer Inc Hedgehog Pathway Inhibitor [EPC] · Smoothened Receptor Antagonists [MoA]
From the FDA label: 1 INDICATIONS AND USAGE DAURISMO is indicated, in combination with low-dose cytarabine, for the treatment of newly-diagnosed acute myeloid leukemia (AML) in adult patients who are ≥75 years old or who have comorbidities that preclude use of…
Lenalidomide · Lenalidomide
Teva Pharmaceuticals, Inc. Thalidomide Analog [EPC]
From the FDA label: 1 INDICATIONS AND USAGE Lenalidomide is a thalidomide analogue indicated for the treatment of adult patients with: Multiple myeloma (MM), in combination with dexamethasone ( 1.1 ). Transfusion-dependent anemia due to low- or intermediate-1-…
MERCAPTOPURINE · Mercaptopurine
Hikma Pharmaceuticals USA Inc. From the FDA label: 1 INDICATIONS AND USAGE Mercaptopurine is a nucleoside metabolic inhibitor indicated for the treatment of patients with acute lymphoblastic leukemia (ALL) as part of a combination chemotherapy maintenance regimen. ( 1.1 ) 1.1 Acute Lymphobl…
NELARABINE · Nelarabine
Alembic Pharmaceuticals Limited Nucleoside Metabolic Inhibitor [EPC] · Nucleic Acid Synthesis Inhibitors [MoA]
From the FDA label: 1 INDICATIONS AND USAGE Nelarabine injection is indicated for the treatment of T-cell acute lymphoblastic leukemia (T-ALL) and T-cell lymphoblastic lymphoma (T-LBL) in adult and pediatric patients age 1 year and older whose disease has not
ONCASPAR · Pegaspargase
Servier Pharmaceuticals LLC Asparagine-specific Enzyme [EPC] · Asparaginase [CS]
From the FDA label: 1 INDICATIONS AND USAGE ONCASPAR is an asparagine specific enzyme indicated as a component of a multi-agent chemotherapeutic regimen for treatment of pediatric and adult patients with: First-line acute lymphoblastic leukemia ( 1.1 ) Acute l…
PURIXAN · Purixan
Nova Laboratories, Ltd From the FDA label: 1 INDICATIONS AND USAGE PURIXAN is a nucleoside metabolic inhibitor indicated for the treatment of patients with acute lymphoblastic leukemia (ALL) as part of a combination chemotherapy maintenance regimen.( 1.1 ) 1.1 Acute Lymphoblastic Le…
Leukine · Sargramostim
Partner Therapeutics, Inc. Leukocyte Growth Factor [EPC] · Granulocyte Colony-Stimulating Factor [CS]
From the FDA label: 1 INDICATIONS AND USAGE LEUKINE is a leukocyte growth factor indicated: To shorten time to neutrophil recovery and to reduce the incidence of severe and life-threatening infections and infections resulting in death following induction chemo…
TABLOID · Thioguanine
Waylis Therapeutics LLC From the FDA label: INDICATIONS AND USAGE a) Acute Nonlymphocytic Leukemias TABLOID brand Thioguanine is indicated for remission induction and remission consolidation treatment of acute nonlymphocytic leukemias. However, it is not recommended for use during ma…
GRAFAPEX · Treosulfan
Medexus Pharma, Inc. From the FDA label: 1 INDICATIONS AND USAGE GRAFAPEX is an alkylating drug indicated for: Use in combination with fludarabine as a preparative regimen for allogeneic hematopoietic stem cell transplantation (alloHSCT) in adult and pediatric patients 1 year of a…
Venclexta · Venetoclax
AbbVie Inc. BCL-2 Inhibitor [EPC] · P-Glycoprotein Inhibitors [MoA]
From the FDA label: 1 INDICATIONS AND USAGE VENCLEXTA is a BCL-2 inhibitor indicated: For the treatment of adult patients with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL). ( 1.1 ) In combination with azacitidine, or decitabine, or lo…