Second Opinion
Second opinion at Mayo Clinic Cancer Center
How it works
Combination of in-person (at Rochester, Scottsdale, or Jacksonville campuses) and remote eConsults (often coordinated through Mayo Clinic Care Network partner hospitals). Direct patient remote second opinions are available in some specialties.
Cost
Published ranges are approximately $500–$2,500 for remote consultations, depending on specialty and complexity. eConsults coordinated through partner hospitals in the Mayo Care Network are sometimes no-cost to the patient (paid by the partner institution). Insurance coverage varies.
Turnaround time
Varies. Remote eConsult through a Mayo Care Network partner: typically 1–2 weeks. Direct appointment: 2–6 weeks scheduling.
What's covered
Multi-site, multi-specialty. Mayo's three campuses each have full oncology services, and remote eConsults span most oncology subspecialties.
When this is a good fit
Patients whose local institution is in the Mayo Clinic Care Network (check directly) can often get a free eConsult. Complex cases benefiting from multi-site specialty depth.
When to consider other options
Patients who want predictable pricing upfront — Mayo's fees vary by case. Cases where you need a fixed-scope asynchronous written report at a known price.
How to request
Related guides
Self-referral process, documents to gather, insurance rules.
Virtual oncology second opinion: what to expect →How remote record review and video consultation work.
Does insurance cover cancer second opinions? →Medicare, Medicare Advantage, PPO, HMO coverage rules.
Second opinion cost comparison →What major centers charge and insurance coverage.
How to request your medical records →HIPAA right-of-access steps. Required before any second opinion.
All NCI-designated cancer centers →72 centers with state browser and CMS quality ratings.