CancerDrs

Multiple Myeloma: drug payment transparency

Multiple myeloma is treated with combinations of drugs from multiple classes, and regimens shift substantially every few years as new agents gain approval. Three-drug versus four-drug induction regimens, maintenance duration, and choice among anti-CD38 antibodies and BCMA-targeted therapies are all active areas of clinical debate where close-substitute options exist.

Data from CMS Open Payments (2023–2024) · last checked

The drugs in question

These are the close-substitute branded therapies your oncologist may choose among for multiple myeloma. Generic and biosimilar options may also be available depending on line of therapy.

Immunomodulatory agents (IMiDs)

  • Revlimid (lenalidomide) — Bristol-Myers Squibb
  • Pomalyst (pomalidomide) — Bristol-Myers Squibb

Proteasome inhibitors

  • Velcade / generic (bortezomib) — Takeda / multiple
  • Kyprolis (carfilzomib) — Amgen
  • Ninlaro (ixazomib) — Takeda

Anti-CD38 monoclonal antibodies

  • Darzalex / Darzalex Faspro (daratumumab) — Johnson & Johnson
  • Sarclisa (isatuximab) — Sanofi

BCMA-targeted therapies

  • Abecma (idecabtagene vicleucel) — Bristol-Myers Squibb / 2seventy bio
  • Carvykti (ciltacabtagene autoleucel) — Johnson & Johnson / Legend Biotech
  • Tecvayli (teclistamab) — Johnson & Johnson
  • Elrexfio (elranatamab) — Pfizer

Top paying manufacturers to oncologists in our index

Across all oncologists in our index (all cancer types), these are the companies making these multiple myeloma drugs, summed across their latest reported year of disclosures. Payments include both general and research categories; see methodology for the split.

Manufacturer Total disclosed to oncologists (latest year)
Pfizer $8,033,132
Takeda $2,358,190
Amgen $1,955,252
Sanofi $852,121
Legend Biotech $120,080
Johnson & Johnson $1,618

multiple myeloma trials with research-payment cross-reference

Active multiple myeloma trials in our database where one or more research-payment records (tied to the trial's NCT ID) are disclosed in CMS Open Payments. We show the disclosed principal investigators and amounts. The presence of research payments on a trial is expected — industry-funded clinical trials pay the physicians running them for site work — but knowing the scale gives you useful context.

Sponsor: Regeneron Pharmaceuticals · sponsor also appears in the payment records

Disclosed research payments

$1,524,060

Named PIs

5

  • ROBERT ORLOWSKI: $785,158
  • CHRISTOPHER FERRERI: $156,663
  • RAJSHEKHAR CHAKRABORTY: $112,471

ClinicalTrials.gov  ·  CMS Open Payments (this trial)

Sponsor: Regeneron Pharmaceuticals · sponsor also appears in the payment records

Disclosed research payments

$104,008

Named PIs

2

  • ELIZABETH O'DONNELL: $75,642
  • MICHAEL SCHUSTER: $28,366

ClinicalTrials.gov  ·  CMS Open Payments (this trial)

+ 9 additional trials with cross-reference data. Browse all multiple myeloma trials →

Questions to ask your oncologist

  • Among the approved options for my stage and biomarker profile, which do you recommend, and why this one over its close substitutes?
  • Have you received consulting, speaking, or research payments from the maker of the drug you're recommending? (Every U.S. physician can look themselves up at openpaymentsdata.cms.gov.)
  • Are there cooperative-group or NIH-sponsored trials I should consider, in addition to industry-sponsored ones?
  • What do the published head-to-head trials show for the option you're recommending versus its substitutes?

A financial relationship between a physician and a manufacturer is not, on its own, a problem — it is the expected context of modern drug development. The purpose of federal disclosure is to let you ask informed questions, not to make the decision for you.

More on multiple myeloma

Medical disclaimer: This page aggregates public federal data and is not medical advice. Drug choice for any individual patient depends on stage, biomarker profile, prior therapy, comorbidities, and patient preference — decisions that must be made with your licensed care team.

About the payment data: Figures are disclosed by manufacturers to CMS under the Physician Payments Sunshine Act (42 U.S.C. §1320a-7h). Presence of payments is not a conflict of interest. Physicians who believe a record is wrong file a correction through the CMS dispute process.

Sources: CMS Open Payments · ClinicalTrials.gov · Data fetched: 2026-04-21 · full methodology