Phase 3 Recruiting Academic/Other
This Phase III Trial will determine whether adjuvant chemotherapy (ACT) added to ovarian function suppression (OFS) plus endocrine therapy (ET) is superior to OFS plus ET in improving invasive breast cancer-free survival (IBCFS) among prem…
Sponsor: NRG Oncology
NCT ID: NCT05879926
Sites in Maine: - Harold Alfond Center for Cancer Care — Augusta, Maine
- MaineHealth Waldo Hospital — Belfast, Maine
- MaineHealth Maine Medical Center - Biddeford — Biddeford, Maine
- Mid Coast Hospital — Brunswick, Maine
- MaineHealth LincolnHealth Hospital — Damariscotta, Maine
Phase 3 Recruiting Academic/Other
This phase III trial compares the effectiveness of fractionated stereotactic radiosurgery (FSRS) to usual care stereotactic radiosurgery (SRS) in treating patients with cancer that has spread from where it first started to the brain. Radia…
Sponsor: NRG Oncology
NCT ID: NCT06500455
Sites in Maine: - MaineHealth Maine Medical Center - Portland — Portland, Maine
- MaineHealth Cancer Care Center of York County — Sanford, Maine
- MaineHealth Maine Medical Center- Scarborough — Scarborough, Maine
Phase 3 Recruiting Industry
This is a Phase III open-label study to assess if camizestrant improves outcomes compared to standard adjuvant endocrine therapy for patients with ER+/HER2- early breast cancer with intermediate-high or high risk for disease recurrence who…
Sponsor: AstraZeneca
NCT ID: NCT05952557
Sites in Maine: - Research Site — Scarborough, Maine
Phase 3 Recruiting Academic/Other
The purpose of this study is to generate evidence on an alternative dosing strategy for CDK4/6 inhibitors to help more patients with Metastatic Breast Cancer (MBC) (age ≥ 65 years) tolerate side effects and stay on treatment longer, to der…
Sponsor: American Society of Clinical Oncology
NCT ID: NCT06377852
Sites in Maine: - The Jackson Laboratory (JAX) - Harold Alfond Center for Cancer Care — Augusta, Maine
- The Jackson Laboratory (JAX) - Northern Light Cancer Care — Brewer, Maine
Phase 3 Recruiting Industry
This is a Phase III, randomized, open-label multicenter study that will evaluate the efficacy and safety of giredestrant compared with fulvestrant, both in combination with the investigator's choice of a CDK4/6 inhibitor (palbociclib, ribo…
Sponsor: Hoffmann-La Roche
NCT ID: NCT06065748
Sites in Maine: - New England Cancer Specialists — Scarborough, Maine
Phase 3 Recruiting Industry
Researchers are looking for new ways to treat types of breast cancer that are both: * High-risk, which means the cancer may have a higher chance of getting worse or coming back after treatment * Early-stage, which means the cancer is in th…
Sponsor: Merck Sharp & Dohme LLC
NCT ID: NCT06966700
Sites in Maine: - New England Cancer Specialists ( Site 0051) — Westbrook, Maine
Phase 3 Recruiting Industry
This is a Phase III trial where participants will be randomized to two treatment groups, which means participants will be assigned by equal chance to a treatment group. This trial will be double-blinded, which means neither the participant…
Sponsor: BioNTech SE
NCT ID: NCT07173751
Sites in Maine: - New England Cancer Specialists — Westbrook, Maine
Phase 2 Recruiting NIH
This ComboMATCH patient screening trial is the gateway to a coordinated set of clinical trials to study cancer treatment directed by genetic testing. Patients with solid tumors that have spread to nearby tissue or lymph nodes (locally adva…
Sponsor: National Cancer Institute (NCI)
NCT ID: NCT05564377
Sites in Maine: - Harold Alfond Center for Cancer Care — Augusta, Maine
- Lafayette Family Cancer Center-EMMC — Brewer, Maine
- MaineHealth Maine Medical Center- Scarborough — Scarborough, Maine
- MaineHealth Cancer Care and IV Therapy - South Portland — South Portland, Maine
Phase 2 Recruiting Academic/Other
This research study is studying how well newly diagnosed breast cancer that has tested positive for a protein called HER2 responds using one of two different combination of HER2-directed therapies as a treatment after surgery. The name of …
Sponsor: Dana-Farber Cancer Institute
NCT ID: NCT04893109
Sites in Maine: - Eastern Maine Medical Center (Northern Light) — Brewer, Maine
- New England Cancer Specialists — Scarborough, Maine
Recruiting Academic/Other
This study collects blood and tissue samples from patients with cancer and without cancer to evaluate tests for early cancer detection. Collecting and storing samples of blood and tissue from patients with and without cancer to study in th…
Sponsor: Alliance for Clinical Trials in Oncology
NCT ID: NCT05334069
Sites in Maine: - Harold Alfond Center for Cancer Care — Augusta, Maine
- MaineHealth Waldo Hospital — Belfast, Maine
- MaineHealth Maine Medical Center - Biddeford — Biddeford, Maine
- Lafayette Family Cancer Center-EMMC — Brewer, Maine
- MaineHealth Cancer Care and IV Therapy - Brunswick — Brunswick, Maine
Recruiting Academic/Other
This is a multi-site clinical study enrolling 2000 newly diagnosed patients with breast, colorectal, melanoma, non-Hodgkin lymphoma, or non-small cell lung cancer, who are planning to receive one or more systemic cancer directed therapies …
Sponsor: Wake Forest University Health Sciences
NCT ID: NCT06418204
Sites in Maine: - Harold Alfond Center for Cancer Care — Augusta, Maine
- MaineHealth Waldo Hospital — Belfast, Maine
- MaineHealth Maine Medical Center - Biddeford — Biddeford, Maine
- MaineHealth Cancer Care and IV Therapy - Brunswick — Brunswick, Maine
- Mid Coast Hospital — Brunswick, Maine