Breast Cancer clinical trials in West Virginia

10 actively recruiting breast cancer trials at 8 sites across West Virginia.

Data from ClinicalTrials.gov · last refreshed 2026-05-25

Phase 3 Recruiting Academic/Other

Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25

This Phase III Trial will determine whether adjuvant chemotherapy (ACT) added to ovarian function suppression (OFS) plus endocrine therapy (ET) is superior to OFS plus ET in improving invasive breast cancer-free survival (IBCFS) among prem…

Sponsor: NRG Oncology

NCT ID: NCT05879926

Sites in West Virginia:

United Hospital Center — Bridgeport, West Virginia
WVUH-Berkely Medical Center — Martinsburg, West Virginia
West Virginia University Healthcare — Morgantown, West Virginia
Camden Clark Medical Center — Parkersburg, West Virginia
Princeton Community Hospital — Princeton, West Virginia

View on ClinicalTrials.gov →

Phase 3 Recruiting Academic/Other

ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab

This phase III trial compares 6 months of human epidermal growth factor receptor 2 (HER2)-targeted therapy to 12 months of HER2-targeted therapy for the treatment of HER2-positive (+) breast cancer in patients that had a pathologic complet…

Sponsor: Alliance for Clinical Trials in Oncology

NCT ID: NCT06876714

Sites in West Virginia:

United Hospital Center — Bridgeport, West Virginia
Edwards Comprehensive Cancer Center — Huntington, West Virginia
Saint Mary's Medical Center — Huntington, West Virginia
WVUH-Berkely Medical Center — Martinsburg, West Virginia
West Virginia University Healthcare — Morgantown, West Virginia

View on ClinicalTrials.gov →

Phase 3 Recruiting Industry

Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)

The goal of this study is to find out if the experimental product, sacituzumab govitecan-hziy (SG) in combination with pembrolizumab given after surgery, is effective and safe compared to the treatment of physician's choice (TPC) which inc…

Sponsor: Gilead Sciences

NCT ID: NCT05633654

Sites in West Virginia:

West Virginia University Hospital — Morgantown, West Virginia

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Phase 3 Recruiting Industry

An Adjuvant Endocrine-based Therapy Study of Camizestrant (AZD9833) in ER+/HER2- Early Breast Cancer (CAMBRIA-2)

This is a Phase III open-label study to assess if camizestrant improves outcomes compared to standard adjuvant endocrine therapy for patients with ER+/HER2- early breast cancer with intermediate-high or high risk for disease recurrence who…

Sponsor: AstraZeneca

NCT ID: NCT05952557

Sites in West Virginia:

Research Site — Charleston, West Virginia
Research Site — Morgantown, West Virginia

View on ClinicalTrials.gov →

Phase 2 Recruiting NIH

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

This ComboMATCH patient screening trial is the gateway to a coordinated set of clinical trials to study cancer treatment directed by genetic testing. Patients with solid tumors that have spread to nearby tissue or lymph nodes (locally adva…

Sponsor: National Cancer Institute (NCI)

NCT ID: NCT05564377

Sites in West Virginia:

West Virginia University Charleston Division — Charleston, West Virginia
Edwards Comprehensive Cancer Center — Huntington, West Virginia
West Virginia University Healthcare — Morgantown, West Virginia

View on ClinicalTrials.gov →

Phase 2 Recruiting Academic/Other

Pioglitazone Therapy Targeting Fatigue in Breast Cancer

The goal of this project is to evaluate the therapeutic potential of pioglitazone (PIO) to target underlying mechanisms that promote muscle fatigue in patients with breast cancer. This represents an off-label use of this compound, both in …

Sponsor: West Virginia University

NCT ID: NCT05013255

Sites in West Virginia:

West Virginia University Cancer Institute — Morgantown, West Virginia

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Recruiting Academic/Other

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

This study collects blood and tissue samples from patients with cancer and without cancer to evaluate tests for early cancer detection. Collecting and storing samples of blood and tissue from patients with and without cancer to study in th…

Sponsor: Alliance for Clinical Trials in Oncology

NCT ID: NCT05334069

Sites in West Virginia:

Edwards Comprehensive Cancer Center — Huntington, West Virginia

View on ClinicalTrials.gov →

Recruiting Industry

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

International registry for cancer patients evaluating the feasibility and clinical utility of an Artificial Intelligence-based precision oncology clinical trial matching tool, powered by a virtual tumor boards (VTB) program, and its clinic…

Sponsor: Massive Bio, Inc.

NCT ID: NCT03452774

Sites in West Virginia:

Massive Bio SYNERGY-AI site — Morgantown, West Virginia

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Recruiting Industry

EXActDNA-003 / NSABP B-64: Study of Molecular Residual Disease Detection in Breast Cancer (MRD)

The EXActDNA-003 study will prospectively enroll participants who are planning to undergo chemotherapy for high-risk, early breast cancer, who are willing to provide tissue and blood specimens for circulating tumor DNA (ctDNA) analysis. Pa…

Sponsor: Exact Sciences Corporation

NCT ID: NCT06401421

Sites in West Virginia:

WVU Cancer Institute — Morgantown, West Virginia

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NA Recruiting Academic/Other

Lifting More Than Weights: Resistance Exercise Program Across Socioeconomic Groups for Cancer-Related Fatigue Management

The long-term goal of this project is to improve the implementation of tailored resistance exercise interventions for Appalachian breast cancer survivors. To achieve this goal, the primary objective is to enhance the understanding of how b…

Sponsor: West Virginia University

NCT ID: NCT06960720

Sites in West Virginia:

West Virginia University — Morgantown, West Virginia

View on ClinicalTrials.gov →

Medical disclaimer: This page aggregates public ClinicalTrials.gov data. It is not medical advice. Always confirm eligibility and enrollment details with the trial site or your oncologist.

Source: ClinicalTrials.gov API v2 · Last checked: 2026-05-25