Phase 2, Phase 3 Recruiting Academic/Other
This phase II/III trial studies how well sentinel lymph node biopsy works and compares sentinel lymph node biopsy surgery to standard neck dissection as part of the treatment for early-stage oral cavity cancer. Sentinel lymph node biopsy s…
Sponsor: NRG Oncology
NCT ID: NCT04333537
Sites in Arizona: - Banner MD Anderson Cancer Center — Gilbert, Arizona
- Mayo Clinic Hospital in Arizona — Phoenix, Arizona
- Banner University Medical Center - Tucson — Tucson, Arizona
- University of Arizona Cancer Center-North Campus — Tucson, Arizona
Phase 3 Recruiting Industry
The purpose of this study is to compare anti-tumor activity of amivantamab in addition to pembrolizumab and carboplatin versus pembrolizumab, 5-fluorouracil (FU), and platinum therapy (carboplatin or cisplatin) in participants with refract…
Sponsor: Janssen Research & Development, LLC
NCT ID: NCT07276399
Sites in Arizona: - Ironwood Cancer and Research Center — Chandler, Arizona
- University of Arizona Cancer Center — Tucson, Arizona
Phase 3 Recruiting Industry
The purpose of this study is to compare the efficacy and safety of ficlatuzumab plus cetuximab compared to placebo plus cetuximab in participants with recurrent/metastatic (R/M) HPV-negative Head and Neck Cancer. The primary hypothesis is …
Sponsor: AVEO Pharmaceuticals, Inc.
NCT ID: NCT06064877
Sites in Arizona: - Banner MD Anderson Cancer Center — Gilbert, Arizona
- The University of Arizona Cancer Center — Tucson, Arizona
Phase 3 Recruiting Industry
This is a phase III, randomized, double-blind, placebo-controlled, multi-center, global study to explore the efficacy and safety of volrustomig in women with high-risk LACC (FIGO 2018 stage IIIA to IVA cervical cancer) who have not progres…
Sponsor: AstraZeneca
NCT ID: NCT06079671
Sites in Arizona: - Research Site — Phoenix, Arizona
- Research Site — Tucson, Arizona
Phase 2 Recruiting Network
This phase II trial studies how well radiation therapy with or without cisplatin works in treating patients with stage III-IVA squamous cell carcinoma of the head and neck who have undergone surgery. Radiation therapy uses high energy x-ra…
Sponsor: ECOG-ACRIN Cancer Research Group
NCT ID: NCT02734537
Sites in Arizona: - Cancer Center at Saint Joseph's — Phoenix, Arizona
- University of Arizona Cancer Center-Orange Grove Campus — Tucson, Arizona
- Banner University Medical Center - Tucson — Tucson, Arizona
- University of Arizona Cancer Center-North Campus — Tucson, Arizona
Phase 2 Recruiting NIH
This phase II trial studies the good and bad effects of the combination of drugs called cabozantinib and nivolumab in treating patients with melanoma or squamous cell head and neck cancer that may have spread from where it first started to…
Sponsor: National Cancer Institute (NCI)
NCT ID: NCT05136196
Sites in Arizona: - Mayo Clinic Hospital in Arizona — Phoenix, Arizona
Phase 2 Recruiting Academic/Other
This phase II trial compares the effectiveness of adding BMX-001 to usual symptom management versus usual symptom management alone for reducing oral mucositis in patients who are receiving chemoradiation for head and neck cancer. Oral muco…
Sponsor: NRG Oncology
NCT ID: NCT06532279
Sites in Arizona: - Arizona Center for Cancer Care - Gilbert — Gilbert, Arizona
- Arizona Center for Cancer Care-Peoria — Peoria, Arizona
- Arizona Center for Cancer Care - Phoenix — Phoenix, Arizona
- Arizona Center for Cancer Care - Scottsdale — Scottsdale, Arizona
- Arizona Center for Cancer Care-Surprise — Surprise, Arizona
Phase 2 Recruiting NIH
This phase II trial tests effects of nivolumab in combination with chemotherapy drugs prior to radiation therapy patients with nasopharyngeal carcinoma (NPC). Immunotherapy with monoclonal antibodies, such as nivolumab, may help the body's…
Sponsor: National Cancer Institute (NCI)
NCT ID: NCT06064097
Sites in Arizona: - Phoenix Childrens Hospital — Phoenix, Arizona
Phase 1, Phase 2 Recruiting Industry
This is a dose-escalation and dose-expansion Phase 1/2a trial to evaluate the safety and tolerability of DB-1311/BNT324 in subjects with advanced solid tumors.
Sponsor: DualityBio Inc.
NCT ID: NCT05914116
Sites in Arizona: - Research Site 111 — Tucson, Arizona
Phase 2 Recruiting Industry
This is a Phase 2 study designed to determine the preliminary anti-tumor activity and confirm the safety of VV1 in combination with cemiplimab. The study will enroll patients with three distinct separate tumor cohorts. The cancers types ar…
Sponsor: Vyriad, Inc.
NCT ID: NCT04291105
Sites in Arizona: - Mayo Clinical — Phoenix, Arizona
Phase 1, Phase 2 Recruiting Academic/Other
BDTX-4933-101 is a first-in-human, open-label, Phase 1/2 dose escalation, dose optimization and expansion study designed to evaluate the safety and tolerability of S241656 as monotherapy and in combination with other anti-cancer therapies …
Sponsor: Institut de Recherches Internationales Servier
NCT ID: NCT05786924
Sites in Arizona: - Banner Health- MD Anderson Cancer Center — Gilbert, Arizona
Phase 1, Phase 2 Recruiting Industry
The goal of this study is to test A2B395, an allogeneic logic-gated Tmod™ CAR T-cell product in subjects with solid tumors including colorectal cancer (CRC), non-small cell lung cancer (NSCLC), head and neck squamous cell carcinoma (HNSCC)…
Sponsor: A2 Biotherapeutics Inc.
NCT ID: NCT06682793
Sites in Arizona: - Banner MD Anderson Cancer Center — Gilbert, Arizona
Phase 1, Phase 2 Recruiting Industry
The purpose of this study is to evaluate the safety, tolerability, pharmacokinetic, pharmacodynamic, preliminary anti-tumor activity, and to determine the recommended Phase II dose (RP2D) of the ALE.P03 monotherapy in adult patients with s…
Sponsor: Alentis Therapeutics AG
NCT ID: NCT07169734
Sites in Arizona: - Mayo Clinic Comprehensive Cancer Center — Phoenix, Arizona
Phase 1, Phase 2 Recruiting Industry
The purpose of this study is to evaluate the safety, tolerability, pharmacokinetic, pharmacodynamic, preliminary anti-tumor activity, and to determine the recommended Phase II dose (RP2D) of the ALE.P02 monotherapy in adult patients with s…
Sponsor: Alentis Therapeutics AG
NCT ID: NCT06747585
Sites in Arizona: - Mayo Foundation for Medical Education and Research - Mayo Cl — Scottsdale, Arizona
Phase 2 Recruiting Academic/Other
This phase II trial examines the use of blood-based biomarkers is to help inform decision making for treatment and radiation therapy for patients with human papillomavirus (HPV) positive oropharyngeal squamous cell cancers. The standard tr…
Sponsor: Mayo Clinic
NCT ID: NCT05541016
Sites in Arizona: - Mayo Clinic in Arizona — Scottsdale, Arizona
Phase 1 Recruiting Industry
The purpose of this study is to find out whether the study drug, LY4170156, is safe, tolerable and effective in participants with advanced solid tumors. The study is conducted in two parts - phase Ia (dose-escalation, dose-optimization) an…
Sponsor: Eli Lilly and Company
NCT ID: NCT06400472
Sites in Arizona: - HonorHealth — Scottsdale, Arizona
Phase 1 Recruiting Academic/Other
Part 1 of this study is an open-label, dose-escalation, and safety expansion study of an anti-LILRB2 / anti-PD-L1 bispecific antibody SPX- 303 in patients with solid tumors. Part 2 of this study is an indication-specific dose expansion stu…
Sponsor: SparX Biotech(Jiangsu) Co., Ltd.
NCT ID: NCT06259552
Sites in Arizona: - Mayo Clinic Arizona — Phoenix, Arizona
- HonorHealth Research and Innovation Institute — Scottsdale, Arizona
Recruiting Academic/Other
This study collects blood and tissue samples from patients with cancer and without cancer to evaluate tests for early cancer detection. Collecting and storing samples of blood and tissue from patients with and without cancer to study in th…
Sponsor: Alliance for Clinical Trials in Oncology
NCT ID: NCT05334069
Sites in Arizona: - Kingman Regional Medical Center — Kingman, Arizona
- Cancer Center at Saint Joseph's — Phoenix, Arizona
NA Recruiting Network
This is a randomized controlled trial to compare survival for patients who undergoe robotic assisted laparoscopy versus open hysterectomy and lymph node assessment for the treatment of early stage cervical cancer.
Sponsor: GOG Foundation
NCT ID: NCT04831580
Sites in Arizona: - Western Regional Medical Center LLC — Goodyear, Arizona
Phase 4 Recruiting Industry
TIVDAK is used for the treatment of cervical cancer that has come back after chemotherapy. Chemotherapy is a treatment that uses medicines to stop the growth of cancer cells. This is done either by killing the cells or by stopping them fro…
Sponsor: Pfizer
NCT ID: NCT06952660
Sites in Arizona: - HonorHealth Cancer Care - Biltmore - AZCCC Imaging — Phoenix, Arizona
- HonorHealth Cancer Care - Biltmore - HonorHealth Research Pharmacy — Phoenix, Arizona
- Sonora Quest Laboratories, LLC — Phoenix, Arizona
- South West Medical Imaging (SMIL) — Phoenix, Arizona
- Schwartz Laser Eye Center — Scottsdale, Arizona
Recruiting Industry
International registry for cancer patients evaluating the feasibility and clinical utility of an Artificial Intelligence-based precision oncology clinical trial matching tool, powered by a virtual tumor boards (VTB) program, and its clinic…
Sponsor: Massive Bio, Inc.
NCT ID: NCT03452774
Sites in Arizona: - Massive Bio SYNERGY-AI site — Scottsdale, Arizona
Recruiting Industry
This study will evaluate the effectiveness of T-DXd in patients with HER2-positive (IHC 3+) locally advanced, unresectable, or metastatic solid tumors who have received prior systemic treatment for metastatic or advanced disease and have n…
Sponsor: AstraZeneca
NCT ID: NCT07124000
Sites in Arizona: - Research Site — Bullhead City, Arizona
- Research Site — Casa Grande, Arizona
Recruiting Academic/Other
This study is being done to collect tissue samples to test how accurately a tumor response platform, Elephas, can predict clinical response across multiple types of immunotherapies, chemoimmunotherapy and tumor types.
Sponsor: Mayo Clinic
NCT ID: NCT06349642
Sites in Arizona: - Mayo Clinic in Arizona — Phoenix, Arizona
Recruiting Academic/Other
This study is being done to identify and differentiate thyroid nodules by acoustic imaging and viscoelastic parameters.
Sponsor: Mayo Clinic
NCT ID: NCT06207188
Sites in Arizona: - Mayo Clinic in Arizona — Scottsdale, Arizona
NA Recruiting Academic/Other
This clinical trial examines the integration of cancer genetic testing in various ethnic populations. Studying individuals and families at risk of cancer may help identify cancer genes and other persons at risk. The information from this s…
Sponsor: Mayo Clinic
NCT ID: NCT04475640
Sites in Arizona: - Mayo Clinic in Arizona — Scottsdale, Arizona