Lymphoma clinical trials in South Dakota

10 actively recruiting lymphoma trials at 6 sites across South Dakota.

Data from ClinicalTrials.gov · last refreshed 2026-10-01

Phase 3 Recruiting NIH

A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab

This phase III trial compares the effect of adding immunotherapy (brentuximab vedotin and nivolumab) to standard treatment (chemotherapy with or without radiation) to the standard treatment alone in improving survival in patients with stag…

Sponsor: National Cancer Institute (NCI)

NCT ID: NCT05675410

Sites in South Dakota:

Sanford USD Medical Center - Sioux Falls — Sioux Falls, South Dakota

View on ClinicalTrials.gov →

Phase 3 Recruiting Academic/Other

Testing Continuous Versus Intermittent Treatment With the Study Drug Zanubrutinib for Older Patients With Previously Untreated Mantle Cell Lymphoma

This phase III trial tests whether continuous or intermittent zanubrutinib after achieving a complete remission (CR) with rituximab works in older adult patients with mantle cell lymphoma (MCL) who have not received treatment in the past (…

Sponsor: Alliance for Clinical Trials in Oncology

NCT ID: NCT05976763

Sites in South Dakota:

Sanford Cancer Center Oncology Clinic — Sioux Falls, South Dakota
Sanford USD Medical Center - Sioux Falls — Sioux Falls, South Dakota

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Phase 3 Recruiting Academic/Other

Testing the Addition of Anti-Cancer Drug Sonrotoclax, to the Standard Treatment Zanubrutinib, for Previously Untreated CLL/SLL

This phase III trial compares the effect of adding sonrotoclax to zanubrutinib versus zanubrutinib alone for the treatment of patients with untreated chronic lymphoblastic leukemia (CLL)/small lymphocytic lymphoma (SLL). Sonrotoclax is in …

Sponsor: Alliance for Clinical Trials in Oncology

NCT ID: NCT07321652

Sites in South Dakota:

Avera Cancer Institute-Aberdeen — Aberdeen, South Dakota
Avera Cancer Institute - Mitchell — Mitchell, South Dakota
Avera Cancer Institute at Pierre — Pierre, South Dakota
Sanford Cancer Center Oncology Clinic — Sioux Falls, South Dakota
Avera Cancer Institute — Sioux Falls, South Dakota

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Phase 3 Recruiting Industry

A Study of Nemtabrutinib Plus Venetoclax vs Venetoclax + Rituximab (VR) in Second-line (2L) + Relapsed/Refractory (R/R) Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) (MK-1026-010/BELLWAVE-010).

The purpose of this study is to assess the safety and tolerability and to confirm the dose of nemtabrutinib in combination with venetoclax in participants with R/R CLL/SLL. The primary study hypotheses are that the combination of nemtabrut…

Sponsor: Merck Sharp & Dohme LLC

NCT ID: NCT05947851

Sites in South Dakota:

Avera Cancer Institute- Research ( Site 5437) — Sioux Falls, South Dakota

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Phase 2 Recruiting NIH

A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL)

This phase II trial studies the effect of nivolumab in combination with blinatumomab compared to blinatumomab alone in treating patients with B-cell acute lymphoblastic leukemia (B-ALL) that has come back (relapsed). Down syndrome patients…

Sponsor: National Cancer Institute (NCI)

NCT ID: NCT04546399

Sites in South Dakota:

Sanford USD Medical Center - Sioux Falls — Sioux Falls, South Dakota

View on ClinicalTrials.gov →

Phase 1, Phase 2 Recruiting Industry

Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)

Substudy 01A is part of a platform study. The purpose of this study is to assess the efficacy and safety of zilovertamab vedotin in pediatric participants with relapsed or refractory B-cell acute lymphoblastic leukemia (B-ALL), diffuse lar…

Sponsor: Merck Sharp & Dohme LLC

NCT ID: NCT06395103

Sites in South Dakota:

Sanford Children's Hospital-Sanford Children's Specialty Clinic ( Site 1015) — Sioux Falls, South Dakota

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Phase 1, Phase 2 Recruiting Industry

A Study of Pembrolizumab (MK-3475) in Pediatric Participants With an Advanced Solid Tumor or Lymphoma (MK-3475-051/KEYNOTE-051)

Researchers are looking for new ways to treat children with different types of melanoma (skin cancer), solid tumors, and lymphomas (blood cancers) that are any of these: * Advanced, which means cancer spread in the body or cannot be remove…

Sponsor: Merck Sharp & Dohme LLC

NCT ID: NCT02332668

Sites in South Dakota:

Call for Information (Investigational Site 0071) — Sioux Falls, South Dakota

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Recruiting Academic/Other

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

This is a multi-site clinical study enrolling 2000 newly diagnosed patients with breast, colorectal, melanoma, non-Hodgkin lymphoma, or non-small cell lung cancer, who are planning to receive one or more systemic cancer directed therapies …

Sponsor: Wake Forest University Health Sciences

NCT ID: NCT06418204

Sites in South Dakota:

Monument Health Rapid City Hospital — Rapid City, South Dakota

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Recruiting Industry

A Longitudinal Multi-Center Molecular Biomarker Discovery Registry for Patients With Hematologic Malignancies

The TEMPUS AQUARIUS Study is a non-interventional, longitudinal observational study focused on hematological malignancies. It will collect rich molecular (multi-omic) and clinical data from patient cohorts through serial blood draws and th…

Sponsor: Tempus AI

NCT ID: NCT07154823

Sites in South Dakota:

Avera Cancer Institue — Sioux Falls, South Dakota

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Recruiting Academic/Other

Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford

CoRDS, or the Coordination of Rare Diseases at Sanford, is based at Sanford Research in Sioux Falls, South Dakota. It provides researchers with a centralized, international patient registry for all rare diseases. This program allows patien…

Sponsor: Sanford Health

NCT ID: NCT01793168

Sites in South Dakota:

Sanford Health — Sioux Falls, South Dakota

View on ClinicalTrials.gov →

Medical disclaimer: This page aggregates public ClinicalTrials.gov data. It is not medical advice. Always confirm eligibility and enrollment details with the trial site or your oncologist.

Source: ClinicalTrials.gov API v2 · Last checked: 2026-10-01