Phase 3 Recruiting Academic/Other
This Phase III Trial will determine whether adjuvant chemotherapy (ACT) added to ovarian function suppression (OFS) plus endocrine therapy (ET) is superior to OFS plus ET in improving invasive breast cancer-free survival (IBCFS) among prem…
Sponsor: NRG Oncology
NCT ID: NCT05879926
Sites in Maine: - Harold Alfond Center for Cancer Care — Augusta, Maine
- MaineHealth Waldo Hospital — Belfast, Maine
- MaineHealth Maine Medical Center - Biddeford — Biddeford, Maine
- Mid Coast Hospital — Brunswick, Maine
- New England Cancer Specialists - Kennebunk — Kennebunk, Maine
Phase 3 Recruiting Academic/Other
This phase III trial compares the effect of olaparib for one year versus two years, with or without bevacizumab, for the treatment of BRCA 1/2 mutated or homologous recombination deficient stage III or IV ovarian cancer. Olaparib is a poly…
Sponsor: NRG Oncology
NCT ID: NCT06580314
Sites in Maine: - MaineHealth Maine Medical Center- Scarborough — Scarborough, Maine
Phase 3 Recruiting Network
This phase III trial studies how well active surveillance help doctors to monitor subjects with low risk germ cell tumors for recurrence after their tumor is removed. When the germ cell tumor has spread outside of the organ in which it dev…
Sponsor: Children's Oncology Group
NCT ID: NCT03067181
Sites in Maine: - Eastern Maine Medical Center — Bangor, Maine
- Lafayette Family Cancer Center-EMMC — Brewer, Maine
- MaineHealth Maine Medical Center - Portland — Portland, Maine
- Maine Children's Cancer Program — Scarborough, Maine
- MaineHealth Maine Medical Center- Scarborough — Scarborough, Maine
Phase 3 Recruiting Network
This phase III trial compares the effect of giving triptorelin vs no triptorelin in preventing ovarian damage in adolescents and young adults (AYAs) with cancer receiving chemotherapy with an alkylating agents. Alkylating agents are part o…
Sponsor: Children's Oncology Group
NCT ID: NCT06513962
Sites in Maine: - Maine Children's Cancer Program — Scarborough, Maine
- MaineHealth Maine Medical Center- Scarborough — Scarborough, Maine
Phase 3 Recruiting Industry
GLORIOSA is a Phase 3 multicenter, open label study designed to evaluate the safety and efficacy of mirvetuximab Soravtansine + Bevacizumab as maintenance therapy in participants with platinum-sensitive ovarian, primary peritoneal or fallo…
Sponsor: AbbVie
NCT ID: NCT05445778
Sites in Maine: - Maine Medical Center - Scarborough Campus /ID# 269555 — Scarborough, Maine
Phase 3 Recruiting Industry
The main goals of this study are to learn about the safety of sacituzumab tirumotecan with bevacizumab and if people tolerate it; and if people who take sacituzumab tirumotecan with or without bevacizumab live longer without the cancer get…
Sponsor: Merck Sharp & Dohme LLC
NCT ID: NCT06824467
Sites in Maine: - Maine Medical Center Research Institute-MaineHealth/Maine Medical Partners - GynOnc ( Site 0008) — Scarborough, Maine
Phase 3 Recruiting Industry
The purpose of this study is to evaluate INCB123667 versus investigator's choice of chemotherapy in participants with platinum-resistant ovarian cancer with cyclin E1 overexpression.
Sponsor: Incyte Corporation
NCT ID: NCT07214779
Sites in Maine: - Maine Center For Cancer Medicine — Scarborough, Maine
Phase 2 Recruiting NIH
This ComboMATCH patient screening trial is the gateway to a coordinated set of clinical trials to study cancer treatment directed by genetic testing. Patients with solid tumors that have spread to nearby tissue or lymph nodes (locally adva…
Sponsor: National Cancer Institute (NCI)
NCT ID: NCT05564377
Sites in Maine: - Harold Alfond Center for Cancer Care — Augusta, Maine
- Lafayette Family Cancer Center-EMMC — Brewer, Maine
- MaineHealth Maine Medical Center- Scarborough — Scarborough, Maine
- MaineHealth Cancer Care and IV Therapy - South Portland — South Portland, Maine
Phase 2 Recruiting NIH
This phase II ComboMATCH treatment trial compares selumetinib plus olaparib to selumetinib alone in women with endometrial or ovarian (fallopian tube and primary peritoneal) cancer that has come back (recurrent) or that remains despite tre…
Sponsor: National Cancer Institute (NCI)
NCT ID: NCT05554328
Sites in Maine: - Harold Alfond Center for Cancer Care — Augusta, Maine
- Lafayette Family Cancer Center-EMMC — Brewer, Maine
- MaineHealth Maine Medical Center- Scarborough — Scarborough, Maine
Recruiting Academic/Other
This study collects blood and tissue samples from patients with cancer and without cancer to evaluate tests for early cancer detection. Collecting and storing samples of blood and tissue from patients with and without cancer to study in th…
Sponsor: Alliance for Clinical Trials in Oncology
NCT ID: NCT05334069
Sites in Maine: - Harold Alfond Center for Cancer Care — Augusta, Maine
- MaineHealth Waldo Hospital — Belfast, Maine
- MaineHealth Maine Medical Center - Biddeford — Biddeford, Maine
- Lafayette Family Cancer Center-EMMC — Brewer, Maine
- MaineHealth Cancer Care and IV Therapy - Brunswick — Brunswick, Maine
NA Recruiting Academic/Other
This clinical trial evaluates how well two surgical procedures (bilateral salpingectomy and bilateral salpingo-oophorectomy) work in reducing the risk of ovarian cancer for individuals with BRCA1 mutations. Bilateral salpingectomy involves…
Sponsor: NRG Oncology
NCT ID: NCT04251052
Sites in Maine: - MaineHealth Maine Medical Center - Portland — Portland, Maine
- MaineHealth Maine Medical Center- Scarborough — Scarborough, Maine
Recruiting Industry
International registry for cancer patients evaluating the feasibility and clinical utility of an Artificial Intelligence-based precision oncology clinical trial matching tool, powered by a virtual tumor boards (VTB) program, and its clinic…
Sponsor: Massive Bio, Inc.
NCT ID: NCT03452774
Sites in Maine: - Massive Bio SYNERGY-AI site — Scarborough, Maine
Recruiting Industry
The purpose of ORACLE is to demonstrate the ability of a novel ctDNA assay developed by Guardant Health to detect recurrence in individuals treated for early-stage solid tumors. It is necessary that ctDNA test results are linked to clinica…
Sponsor: Guardant Health, Inc.
NCT ID: NCT05059444
Sites in Maine: - Central Maine Medical Center — Lewiston, Maine