Phase 1, Phase 2 Recruiting Industry
Phase 1 dose escalation will determine the first cycle dose-limiting toxicities (DLTs), the maximum tolerated dose (MTD), the biologically effective dose and recommended Phase 2 dose (RP2D) of repotrectinib given to adult subjects with adv…
Sponsor: Turning Point Therapeutics, Inc.
NCT ID: NCT03093116
Sites in New York: - Local Institution - 2117 — New York, New York
- Local Institution - 1002 — New York, New York
- Local Institution - 2102 — New York, New York
Phase 2 Recruiting Industry
The objective of this Master Protocol is to evaluate the efficacy and safety of plixorafenib in participants with BRAF altered (BRAF V600E or BRAF fusions) locally advanced or metastatic solid tumors, or recurrent or progressive primary ce…
Sponsor: Fore Biotherapeutics
NCT ID: NCT05503797
Sites in New York: - Columbia University Irving Medical Center — New York, New York
- Memorial Sloan Kettering Cancer Center — New York, New York
Phase 1, Phase 2 Recruiting Academic/Other
BDTX-4933-101 is a first-in-human, open-label, Phase 1/2 dose escalation, dose optimization and expansion study designed to evaluate the safety and tolerability of S241656 as monotherapy and in combination with other anti-cancer therapies …
Sponsor: Institut de Recherches Internationales Servier
NCT ID: NCT05786924
Sites in New York: - NYU Langone Medical Center - Perlmutter Cancer Center (NYU Cancer Institute) — New York, New York
- Memorial Sloan Kettering Cancer Center — New York, New York
Phase 2 Recruiting Academic/Other
The researchers are doing this study to find out if the combination of avutometinib and defactinib is an effective treatment for RAF dimer-driven radioiodine-refractory differentiated thyroid cancer or anaplastic thyroid cancer. The resear…
Sponsor: Memorial Sloan Kettering Cancer Center
NCT ID: NCT06007924
Sites in New York: - Memorial Sloan Kettering Cancer Center Suffolk - Commack (Limited Protocol Activities) — Commack, New York
- Memorial Sloan Kettering Westchester (Limited Protocol Activities) — Harrison, New York
- Memorial Sloan Kettering Cancer Center (All Protocol Activities) — New York, New York
- Memorial Sloan Kettering Nassau (Limited Protocol Activities) — Rockville Centre, New York
Phase 1 Recruiting Industry
The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics (PK), and preliminary efficacy of KIN-2787 in adults with BRAF/NRAS-mutated advanced or metastatic solid tumors.
Sponsor: Pierre Fabre Medicament
NCT ID: NCT04913285
Sites in New York: - NYU Langone — New York, New York
Phase 1 Recruiting Academic/Other
The purpose of this study is to evaluate a new diagnostic imaging test, positron emission tomography (PET), with a different radioactive form of iodine called iodine-124. This form is able to accurately measure the amount of radioactive io…
Sponsor: Memorial Sloan Kettering Cancer Center
NCT ID: NCT03647358
Sites in New York: - Memorial Sloan Kettering Cancer Center — New York, New York
Phase 1 Recruiting Academic/Other
The purpose of this study is to test the safety and effectiveness of using brodalumab in patients who develop side effects from cancer immune therapy. Immune-related side effects are due to activation of the immune system in patients who p…
Sponsor: Brian Henick, MD
NCT ID: NCT06673329
Sites in New York: - Columbia University Irving Medical Center — New York, New York
Recruiting Academic/Other
This study collects blood and tissue samples from patients with cancer and without cancer to evaluate tests for early cancer detection. Collecting and storing samples of blood and tissue from patients with and without cancer to study in th…
Sponsor: Alliance for Clinical Trials in Oncology
NCT ID: NCT05334069
Sites in New York: - Elmhurst Hospital Center — Elmhurst, New York
- Arnot Ogden Medical Center/Falck Cancer Center — Elmira, New York
- Glens Falls Hospital — Glens Falls, New York
- Queens Hospital Center — Jamaica, New York
- NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center — New York, New York
Recruiting Academic/Other
The iCaRe2 is a multi-institutional resource created and maintained by the Fred \& Pamela Buffett Cancer Center to collect and manage standardized, multi-dimensional, longitudinal data and biospecimens on consented adult cancer patients, h…
Sponsor: University of Nebraska
NCT ID: NCT02012699
Sites in New York: - C.R. Wood Cancer Center, Glens Falls Hospital — Glens Falls, New York
- Faxton St. Luke's Healthcare, Mohawk Valley — Utica, New York
NA Recruiting Academic/Other
The researchers are doing this study to see how well a type of ultrasound imaging called multiparametric ultrasound (mpUS), can be used to examine, evaluate, and provide information about different cancerous and non-cancerous tissue. The r…
Sponsor: Memorial Sloan Kettering Cancer Center
NCT ID: NCT07270237
Sites in New York: - Memorial Sloan Kettering Suffolk - Commack (Limited Protocol Activities) — Commack, New York
- Memorial Sloan Kettering Westchester (Consent Only) — Harrison, New York
- Memorial Sloan Kettering Cancer Center (All Protocol Activities) — New York, New York
- Memorial Sloan Kettering Nassau (Consent Only) — Uniondale, New York
NA Recruiting Industry
The primary objective of this study is to reproduce in a multi-center study results obtained during the feasibility First-In-Human (FIH) study with Prof. Stefano Spiezia, MD (Ospedale del Mare, Naples, Italy) and to monitor additional thyr…
Sponsor: Pulse Biosciences, Inc.
NCT ID: NCT07287176
Sites in New York: - NYU Langone Health — New York, New York
- Weill Cornell Medicine — New York, New York
Recruiting Academic/Other
The purpose of this research study is to see if the amount of vitamin D in ones blood makes it more or less likely to develop thyroid gland toxicity when being treated with immunotherapy that blocks the activity of proteins called programe…
Sponsor: Icahn School of Medicine at Mount Sinai
NCT ID: NCT04615988
Sites in New York: - Mount Sinai Hospital /Tisch Cancer Cancer/Ruttenberg Treatment Center — New York, New York
Recruiting Academic/Other
The purpose of this study to learn more about the use of redifferentiating medications as a standard treatment for radioactive iodine/RAI-refractory thyroid cancer. This study is a registry study.
Sponsor: Memorial Sloan Kettering Cancer Center
NCT ID: NCT05733013
Sites in New York: - Memorial Sloan Kettering Cancer Center — New York, New York
NA Recruiting Academic/Other
Patients with small favorable malignant or indeterminate thyroid nodules will receive information about management of thyroid nodules. Participants will be asked to complete brief surveys at the time of enrollment, shortly after the consul…
Sponsor: Stony Brook University
NCT ID: NCT05264857
Sites in New York: - Stony Brook University Cancer Center — Stony Brook, New York
Recruiting Academic/Other
The purpose of this observational research is to evaluate and compare clinical outcomes after treatment for symptomatic benign multinodular goiter (MNG) patients. This is a data collection study in which we ask participants to give access …
Sponsor: Columbia University
NCT ID: NCT05189314
Sites in New York: - Columbia University — New York, New York
NA Recruiting Academic/Other
The purpose of this study is to find out if Meaning-Centered Psychotherapy for Latinos (MCP-L) helps reduce anxiety and depression and improves quality of life compared to cognitive behavioral therapy (CBT). Investigators also want to lear…
Sponsor: Memorial Sloan Kettering Cancer Center
NCT ID: NCT07225309
Sites in New York: - Memorial Sloan Kettering Cancer Center — New York, New York
Recruiting Academic/Other
Magnetic resonance imaging (MRI) is a diagnostic technique that takes pictures of organs of the body. It uses magnetic fields and radio waves that cannot be felt. This makes specific organs, blood vessels, or tumors easier to see. Diffusio…
Sponsor: Memorial Sloan Kettering Cancer Center
NCT ID: NCT03483337
Sites in New York: - Memorial Sloan Kettering Cancer Center — New York, New York
NA Recruiting Academic/Other
Benign thyroid nodules can still create cosmetic, compressive, or hormonal issues for patients. In the past, surgery was typically used to treat thyroid nodules causing the above issues through partial or complete thyroidectomy. More recen…
Sponsor: Northwell Health
NCT ID: NCT05903196
Sites in New York: - Northwell Health Physician Partners — New York, New York
Recruiting Academic/Other
Thyroid cancer incidence has been steadily increasing and has nearly tripled since the 1970's in the US and worldwide. Early detection of small, papillary thyroid cancers using high quality diagnostic imaging explains only about 50% of thi…
Sponsor: Icahn School of Medicine at Mount Sinai
NCT ID: NCT05172921
Sites in New York: - Icahn School of Medicine at Mount Sinai — New York, New York