CancerDrs

Colorectal Cancer clinical trials in Delaware

8 actively recruiting colorectal cancer trials at 7 sites across Delaware.

Data from ClinicalTrials.gov · last refreshed

Phase 2, Phase 3 Recruiting Academic/Other

Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease

This Phase II/III trial will evaluate the what kind of chemotherapy to recommend to patients based on the presence or absences of circulating tumor DNA (ctDNA) after surgery for colon cancer.

Sponsor: NRG Oncology
NCT ID: NCT05174169
Sites in Delaware:
  • Bayhealth Hospital Kent Campus — Dover, Delaware
  • Bayhealth Hospital Sussex Campus — Milford, Delaware
  • Helen F Graham Cancer Center — Newark, Delaware
  • Medical Oncology Hematology Consultants PA — Newark, Delaware
Phase 2 Recruiting Academic/Other

Testing the Addition of Total Ablative Therapy to Usual Systemic Therapy Treatment for Limited Metastatic Colorectal Cancer, ERASur Trial

This phase III trial compares the addition of total ablative therapy to the usual systemic therapy versus the usual systemic therapy alone in treating patients with advanced colorectal cancer that has spread to up to 4 body sites (limited …

Sponsor: Alliance for Clinical Trials in Oncology
NCT ID: NCT05673148
Sites in Delaware:
  • Beebe Medical Center — Lewes, Delaware
  • Beebe South Coastal Health Campus — Millville, Delaware
  • Helen F Graham Cancer Center — Newark, Delaware
  • Medical Oncology Hematology Consultants PA — Newark, Delaware
  • Christiana Care Health System-Christiana Hospital — Newark, Delaware
Phase 1, Phase 2 Recruiting Industry

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

The Phase 2 monotherapy portion of this study is currently enrolling and will evaluate the efficacy and safety of PC14586 (INN rezatapopt) in participants with locally advanced or metastatic solid tumors harboring a TP53 Y220C mutation. Th…

Sponsor: PMV Pharmaceuticals, Inc
NCT ID: NCT04585750
Sites in Delaware:
  • Medical Oncology Hematology Consultants — Newark, Delaware
Phase 2 Recruiting Industry

Evaluation of RBS2418 in Patients With Advanced, Metastatic, and Progressive Colorectal Cancer

RBS2418 is a specific immune modulator that works through the inhibition of ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1) and is designed to lead to anti-tumor immunity by protecting endogenous 2'-3'-cyclic guanosine monophosp…

Sponsor: Riboscience, LLC.
NCT ID: NCT06824064
Sites in Delaware:
  • Christiana Care — Newark, Delaware
Phase 1 Recruiting Industry

Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors

This is a multicenter Phase 1b, open label, dose-escalation and cohort-expansion study, evaluating the safety, tolerability, pharmacokinetics (PK), preliminary antitumor activity, and effect of biomarkers of zanzalintinib administered alon…

Sponsor: Exelixis
NCT ID: NCT05176483
Sites in Delaware:
  • Exelixis Clinical Site #49 — Newark, Delaware
Recruiting Academic/Other

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

This is a multi-site clinical study enrolling 2000 newly diagnosed patients with breast, colorectal, melanoma, non-Hodgkin lymphoma, or non-small cell lung cancer, who are planning to receive one or more systemic cancer directed therapies …

Sponsor: Wake Forest University Health Sciences
NCT ID: NCT06418204
Sites in Delaware:
  • Beebe South Coastal Health Campus — Millville, Delaware
  • Helen F Graham Cancer Center — Newark, Delaware
  • Medical Oncology Hematology Consultants PA — Newark, Delaware
  • Beebe Health Campus — Rehoboth Beach, Delaware
Recruiting Academic/Other

LOTUS-CC: An Observational Research Study to Uncover Subtypes of Cancer Cachexia

This study evaluates cancer-related weight and muscle mass loss, symptoms, and physical function (cachexia) in patients undergoing treatment for colorectal, lung, or pancreatic cancer that cannot be removed by surgery (unresectable) or is …

Sponsor: University of Rochester
NCT ID: NCT06073431
Sites in Delaware:
  • Beebe South Coastal Health Campus — Millville, Delaware
  • Helen F Graham Cancer Center — Newark, Delaware
  • Medical Oncology Hematology Consultants PA — Newark, Delaware
  • Christiana Care Health System-Christiana Hospital — Newark, Delaware
  • Beebe Health Campus — Rehoboth Beach, Delaware
Phase 4 Recruiting Industry

A Trial to Evaluate the Safety and Activity of Fruquintinib in Minority Populations With Advanced, Previously Treated Colorectal Cancer

High blood pressure (hypertension) is a known side effect of the treatment with fruquintinib. Current research does not provide a clear answer whether minority groups such as Black/African American and/or Hispanic/Latino with refractory me…

Sponsor: Takeda
NCT ID: NCT06562543
Sites in Delaware:
  • Christiana Care Health Services — Newark, Delaware

Medical disclaimer: This page aggregates public ClinicalTrials.gov data. It is not medical advice. Always confirm eligibility and enrollment details with the trial site or your oncologist.

Source: ClinicalTrials.gov API v2 · Last checked: 2026-09-07