Phase 3 Recruiting Network
This phase III trial studies whether inotuzumab ozogamicin added to post-induction chemotherapy and immunotherapy (chemo-immunotherapy) for patients with High-Risk B-cell Acute Lymphoblastic Leukemia (B-ALL) improves outcomes. Inotuzumab o…
Sponsor: Children's Oncology Group
NCT ID: NCT03959085
Sites in Nevada: - University Medical Center of Southern Nevada — Las Vegas, Nevada
- Sunrise Hospital and Medical Center — Las Vegas, Nevada
- Alliance for Childhood Diseases/Cure 4 the Kids Foundation — Las Vegas, Nevada
- Summerlin Hospital Medical Center — Las Vegas, Nevada
- Renown Regional Medical Center — Reno, Nevada
Phase 3 Recruiting Network
This phase III trial compares standard chemotherapy to therapy with liposome-encapsulated daunorubicin-cytarabine (CPX-351) and/or gilteritinib for patients with newly diagnosed acute myeloid leukemia with or without FLT3 mutations. Drugs …
Sponsor: Children's Oncology Group
NCT ID: NCT04293562
Sites in Nevada: - University Medical Center of Southern Nevada — Las Vegas, Nevada
- Sunrise Hospital and Medical Center — Las Vegas, Nevada
- Alliance for Childhood Diseases/Cure 4 the Kids Foundation — Las Vegas, Nevada
- Summerlin Hospital Medical Center — Las Vegas, Nevada
- Renown Regional Medical Center — Reno, Nevada
Phase 3 Recruiting Industry
This is a Phase 3, randomized, open-label, multicenter study comparing rocbrutinib (LP-168) versus pirtobrutinib in adult participants with relapsed or refractory chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) who h…
Sponsor: Newave Pharmaceutical Inc
NCT ID: NCT07342478
Sites in Nevada: - Optum Medical Group (Rhodes) P.C. — Las Vegas, Nevada
Phase 2 Recruiting NIH
This phase II trial studies how well inotuzumab ozogamicin and blinatumomab with or without ponatinib work in treating patients with CD22-positive B-lineage acute lymphoblastic leukemia that is newly diagnosed, has come back after a period…
Sponsor: National Cancer Institute (NCI)
NCT ID: NCT03739814
Sites in Nevada: - Carson Tahoe Regional Medical Center — Carson City, Nevada
- Cancer and Blood Specialists-Henderson — Henderson, Nevada
- Comprehensive Cancer Centers of Nevada - Henderson — Henderson, Nevada
- Comprehensive Cancer Centers of Nevada-Horizon Ridge — Henderson, Nevada
- Las Vegas Cancer Center-Henderson — Henderson, Nevada
Phase 2 Recruiting NIH
This phase II MyeloMATCH treatment trial tests whether the standard approach of cytarabine and daunorubicin in comparison to the following experimental regimens works to shrink cancer in patients with high risk acute myeloid leukemia (AML)…
Sponsor: National Cancer Institute (NCI)
NCT ID: NCT05554406
Sites in Nevada: - OptumCare Cancer Care at Charleston — Las Vegas, Nevada
- OptumCare Cancer Care at Fort Apache — Las Vegas, Nevada
Phase 2 Recruiting NIH
This phase II trial studies the effect of nivolumab in combination with blinatumomab compared to blinatumomab alone in treating patients with B-cell acute lymphoblastic leukemia (B-ALL) that has come back (relapsed). Down syndrome patients…
Sponsor: National Cancer Institute (NCI)
NCT ID: NCT04546399
Sites in Nevada: - Carson Tahoe Regional Medical Center — Carson City, Nevada
- Comprehensive Cancer Centers of Nevada - Henderson — Henderson, Nevada
- Comprehensive Cancer Centers of Nevada-Horizon Ridge — Henderson, Nevada
- Las Vegas Cancer Center-Henderson — Henderson, Nevada
- Comprehensive Cancer Centers of Nevada-Southeast Henderson — Henderson, Nevada
Phase 1, Phase 2 Recruiting Academic/Other
This study aims to use clinical and biological characteristics of acute leukemias to screen for patient eligibility for available pediatric leukemia sub-trials. Testing bone marrow and blood from patients with leukemia that has come back a…
Sponsor: PedAL BCU, LLC
NCT ID: NCT04726241
Sites in Nevada: - Alliance for Childhood Diseases/Cure 4 the Kids Foundation — Las Vegas, Nevada
- Summerlin Hospital Medical Center — Las Vegas, Nevada
- Renown Regional Medical Center — Reno, Nevada
Phase 2 Recruiting NIH
This pilot trial assesses the effect of the combination of blinatumomab with dasatinib or imatinib and standard chemotherapy for treating patients with Philadelphia chromosome positive (Ph+) or ABL-class Philadelphia chromosome-like (Ph-li…
Sponsor: National Cancer Institute (NCI)
NCT ID: NCT06124157
Sites in Nevada: - Alliance for Childhood Diseases/Cure 4 the Kids Foundation — Las Vegas, Nevada
Phase 2 Recruiting NIH
This phase II trial tests the addition of venetoclax and/or blinatumomab to usual chemotherapy for treating infants with newly diagnosed acute lymphoblastic leukemia (ALL) with a KMT2A gene rearrangement (KMT2A-rearranged \[R\]) or without…
Sponsor: National Cancer Institute (NCI)
NCT ID: NCT06317662
Sites in Nevada: - Alliance for Childhood Diseases/Cure 4 the Kids Foundation — Las Vegas, Nevada
Phase 2 Recruiting Industry
The main purpose of Part 1 of this study is to assess the efficacy and safety of 3 dose levels of Pirtobrutinib in participants with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL), who have received 1-3 lines of tre…
Sponsor: Loxo Oncology, Inc.
NCT ID: NCT06588478
Sites in Nevada: - Comprehensive Cancer Centers of Nevada — Henderson, Nevada
Recruiting Academic/Other
This study collects blood and tissue samples from patients with cancer and without cancer to evaluate tests for early cancer detection. Collecting and storing samples of blood and tissue from patients with and without cancer to study in th…
Sponsor: Alliance for Clinical Trials in Oncology
NCT ID: NCT05334069
Sites in Nevada: - Carson Tahoe Regional Medical Center — Carson City, Nevada
- Cancer and Blood Specialists-Henderson — Henderson, Nevada
- Comprehensive Cancer Centers of Nevada - Henderson — Henderson, Nevada
- Comprehensive Cancer Centers of Nevada-Horizon Ridge — Henderson, Nevada
- Las Vegas Cancer Center-Henderson — Henderson, Nevada
Recruiting Network
This clinical trial keeps track of and collects follow-up information from patients who are currently enrolled on or have participated in a Children's Oncology Group study. Developing a way to keep track of patients who have participated i…
Sponsor: Children's Oncology Group
NCT ID: NCT00736749
Sites in Nevada: - University Medical Center of Southern Nevada — Las Vegas, Nevada
- Sunrise Hospital and Medical Center — Las Vegas, Nevada
- Alliance for Childhood Diseases/Cure 4 the Kids Foundation — Las Vegas, Nevada
- Summerlin Hospital Medical Center — Las Vegas, Nevada
Recruiting Network
This study attempts to learn more about the health of persons with Down syndrome after treatment for acute leukemia. Children with Down syndrome are at increased risk for side effects during treatment for acute leukemia, but it is unclear …
Sponsor: Children's Oncology Group
NCT ID: NCT05702645
Sites in Nevada: - University Medical Center of Southern Nevada — Las Vegas, Nevada
- Sunrise Hospital and Medical Center — Las Vegas, Nevada
- Alliance for Childhood Diseases/Cure 4 the Kids Foundation — Las Vegas, Nevada
- Summerlin Hospital Medical Center — Las Vegas, Nevada
- Renown Regional Medical Center — Reno, Nevada
Recruiting Network
This clinical trial studies the effects of dexrazoxane hydrochloride on biomarkers associated with cardiomyopathy and heart failure after cancer treatment. Studying samples of blood in the laboratory from patients receiving dexrazoxane hyd…
Sponsor: Children's Oncology Group
NCT ID: NCT01790152
Sites in Nevada: - University Medical Center of Southern Nevada — Las Vegas, Nevada
- Sunrise Hospital and Medical Center — Las Vegas, Nevada
- Alliance for Childhood Diseases/Cure 4 the Kids Foundation — Las Vegas, Nevada
- Summerlin Hospital Medical Center — Las Vegas, Nevada